Zogulitsa
Retinoic Acid
Zomangamanga Formula
Maonekedwe:Kuwala lalanje kapena chikasu crystalline ufa
Kuchulukana:1.0597 (kuyerekeza movutikira)
Malo osungunuka:180-181°C (lit.)
Malo otentha:381.66°C (kuyerekeza molakwika)
Refractivity:1.4800 (chiyerekezo)
Data Data
wamba
Kugwiritsa ntchito
Retinoic acid (tretinoin) ndi yochokera ku vitamini A.Zawonetsa kuthekera kosintha kaphatikizidwe ka collagen, kukulitsa ma dermal hyaluronic acid, ndikulimbikitsa kukula kwa fibroblast ndi matrix a extracellular.Amagwiritsidwa ntchito pochiza matenda a keratinization komanso kuchiza ziphuphu.
Vitamini A, wokhala ndi mamolekyulu a C20H28O2, ndi gawo lapakati la vitamini A m'thupi, lomwe limakhudza kukula kwa mafupa ndikulimbikitsa kagayidwe kachakudya ka epithelial cell proliferation, differentiation and keratinolysis.Amagwiritsidwa ntchito pochiza acne vulgaris, psoriasis, ichthyosis, lichen planus, tsitsi lofiira furunculosis, follicular keratosis, squamous cell carcinoma ndi melanoma.
Category: Anti-skin keratinisation abnormalities, cell inducing differentiation agents
Kusungirako zinthu: kuwala ndi losindikizidwa
Retinoic asidi alibe mphamvu pa ntchito tyrosinase ndi melanin zikuchokera yachibadwa anthu melanocytes.Pamene khungu likukumana ndi ukalamba wokhudza thupi kapena kuonongeka ndi mankhwala, UV cheza kapena zoopsa, retinoic asidi amakonza kapena kupewa sali bwino mu zamankhwala amuzolengedwa zikuchokera ndi morphological dongosolo la dermal connective minofu chifukwa cha zinthu zoipa.Retinoic asidi alibe mphamvu pa yachibadwa khungu kolajeni synthesis.Kuphatikiza apo, retinoic acid imakhala ndi ntchito yoletsa pa leukocyte chemotaxis, motero imakhala ngati anti-inflammatory agent.Retinoic asidi alibe mwachindunji zotsatira pa zopangitsa sebaceous ndi katulutsidwe awo.
