P-Nitroacetophenone

Kufotokozera Kwachidule:

Pakati pa kaphatikizidwe ka organic ndi kaphatikizidwe ka mankhwala (monga synthomycin, chloramphenicol).Amagwiritsidwanso ntchito popanga mankhwala ophera tizilombo, utoto ndi zonunkhira.

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Zambiri Zamalonda

CAS NO: 100-19-6

Kuyera: ≥99%

Fomula: C8H7NO3

Fomu Wt: 165.15

Dzina la Mankhwala: 4-Nitroacetophenone;

4'-Nitroacetophenone;p-Nitroacetophenone

Dzina la IUPAC: 1-(4-nitrophenyl)thanone;

Ethanone, 1-(4-nitrophenyl)-

Malo osungunuka: 75-78 ° C

Malo otentha: 202°C

Phokoso la Flash: 201-202°C

Maonekedwe: Prism yachikasu kapena ufa wonyezimira wachikasu

Kutumiza ndi Kusunga

Kutentha kwa Malo: Kutentha kwa Zipinda

P-nitroacetophenone ndi yofunika yapakatikati mu kaphatikizidwe organic ndipo ntchito ngati zopangira kwa synthesis wa chlortetracycline ndi chloramphenicol mankhwala.Njira yachikale yopangira p-nitroacetophenone ndi oxidation ya ethylbenzene.Kuphatikiza pa chinthu chachikulu cha p-nitroacetophenone, palinso zinthu zina monga p-nitrobenzoic acid mu reaction system.Kupanga madzi otayira kumakhala ndi izi: ① ndende yayikulu, acidity yamphamvu, mtundu wakuda ndi kawopsedwe wamkulu;② Mapangidwe a pawiri m'madzi onyansa ndi okhazikika komanso osawonongeka mosavuta, kotero njira zambiri monga activated carbon adsorption, electrolysis ndi mpweya sizingakwaniritse zomwe mukufuna.Resin adsorbent ili ndi mphamvu yotsatsira komanso kusinthika, ndipo mawonekedwe ake akuthupi ndi mankhwala amakhala okhazikika ndipo amatha kugwiritsidwa ntchito mobwerezabwereza.
Katundu
Chovala choyera ndi kristalo wonyezimira wachikasu kapena kristalo wa singano.Malo osungunuka 80 ~ 82 ℃.Malo otentha 202 ℃.Amasungunuka momasuka mu ethanol yotentha, ether ndi benzene, osasungunuka m'madzi.
Kukonzekera
Ethylbenzene imapangidwa ndi nitrated acid pa 30～35℃ kuti ipeze nitroethylbenzene.Pambuyo pa distillation, p-nitroethylbenzene ndi co-product o-nitroethylbenzene amapezeka.Pamaso pa catalyst cobalt stearate, p-nitroethylbenzene ndi oxidized ndi mpweya pa 140-150 ℃ ndi 0.2MPa kuthamanga kupeza p-nitroacetophenone.The anachita mankhwala anatsukidwa ndi madzi, neutralized, centrifuged ndi madzi, ndi zouma kupereka yomalizidwa mankhwala.
p-Nitrobenzoyl kloride njira.
Chitetezo
Poizoni sichidziwika.Zida zopangira ziyenera kukhala zosatulutsa mpweya ndipo wogwiritsa ntchito azivala zida zodzitetezera.
Amayikidwa mu ng'oma zachitsulo kapena ng'oma zamatabwa zokhala ndi matumba apulasitiki.Kusunga pa youma ndi mpweya wokwanira malo.