Zogulitsa
Adenosine
Zomangamanga Formula
Maonekedwe: ufa wa crystalline woyera kapena woyera-crystalline ufa
Kachulukidwe: 2.08 g/cm³
Malo osungunuka: 234 mpaka 236 ℃
Malo otentha: 676.3 ℃
kusinthika: 1.907
Kung'anima: 362.8 ℃
Data Data
Gulu lowopsa.
Nambala Yoyendetsa Katundu Woopsa.
Wonyamula gulu.
Kugwiritsa ntchito
Adenosine amagwiritsidwa ntchito kuthandizira kubwezeretsa kugunda kwa mtima kwa anthu omwe ali ndi vuto linalake la mtima.
Adenosine imagwiritsidwanso ntchito poyesa kupsinjika kwa mtima.
Adenosine itha kugwiritsidwanso ntchito pazinthu zomwe sizinalembedwe mu bukhuli lamankhwala.
Adenosine, gulu lopangidwa ndi N-9 la adenine logwirizanitsidwa ndi C-1 ya D-ribose ndi β-glycosidic bond, ili ndi mankhwala a C10H13N5O4 ndipo phosphate ester yake ndi adenosine acid.Adenosine ndi amkati nucleoside kuti kufalikira mu maselo a anthu ndipo akhoza mwachindunji kulowa myocardium kupanga adenosine asidi ndi phosphorylation, amene nawo m`mnyewa wamtima mphamvu kagayidwe, komanso dilating mitsempha ya m`mitsempha ndi kuwonjezeka magazi.Amagwiritsidwa ntchito pochiza tachycardia ya supraventricular.Adenosine imakhala ndi zotsatira za thupi pamtima ndi machitidwe ena ambiri ndi minofu ya minofu.Adenosine ndizofunikira zapakatikati zomwe zimagwiritsidwa ntchito popanga adenosine triphosphate (ATP), adenine, adenosine acid, ndi adenosine asiaticum.
Ndi antiarrhythmic wothandizira omwe amasintha paroxysmal supraventricular tachycardia kukhala sinus rhythm.Amagwiritsidwa ntchito ngati supraventricular arrhythmias yokhudzana ndi atrioventricular.Chithandizo cha angina pectoris, m`mnyewa wamtima infarction, mitima insufficiency, atherosclerosis, zofunika matenda oopsa, cerebrovascular matenda, pambuyo sitiroko sequelae, kupita patsogolo minofu atrophy, etc. Amagwiritsidwanso ntchito biochemical maphunziro.
Adenosine ndi endogenous purine nucleoside yomwe imachedwetsa AV node conduction, imatchinga njira ya AV nodal fold, ndikubwezeretsanso kachirombo ka sinus kwa odwala omwe ali ndi paroxysmal supraventricular tachycardia (PSVT) (omwe ali ndi kapena opanda preexcitation syndrome).Adenosine imatengedwa mwachangu ndi maselo ofiira amagazi ndipo chifukwa chake imakhala ndi nthawi yayitali, ndi theka la moyo wa plasma wosakwana 10 s.Mtundu wodziwika bwino wa PSVT ndi kudzera munjira yobwereranso, kotero adenosine imathandiza kuthetsa mtundu uwu wa arrhythmia.Mu non-atrial kapena sinus node regressive arrhythmias (mwachitsanzo, flutter ya atria, fibrillation ya atrial, tachycardia yamagazi, tachycardia yam'mitsempha), adenosine sichiwathetsa, koma imatha kutulutsa kwakanthawi kwa atrioventricular kapena ventricle block, yomwe ingathandize kupanga matenda osiyanasiyana.
